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Polyoxovanadate-iodobodipy supramolecular assemblies: new agents for high efficiency cancer photochemotherapy

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Abstract

Two novel polyoxovanadate-iodoBodipy supramolecular assemblies, named as (2I-BDP-C6)2V6 and (2I-BDP-C6)3V10, were first synthesized by the self-assembly of anionic hexavanadate and decavanadate with cationic iodoBodipy for photochemotherapy, respectively. The mechanisms for synergistic photochemotherapy of the anion–cation pairs were determined. In particular, (2I-BDP-C6)3V10 can effectively kill lung cancer cells (HepG2) by synergetic chemotherapy as well as photodynamic therapy.

Graphical abstract: Polyoxovanadate-iodobodipy supramolecular assemblies: new agents for high efficiency cancer photochemotherapy

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Article information


Submitted
23 Dec 2019
Accepted
31 Jan 2020
First published
05 Feb 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Polyoxovanadate-iodobodipy supramolecular assemblies: new agents for high efficiency cancer photochemotherapy

Y. Gu, Q. Li, Y. Huang, Y. Zhu, Y. Wei and L. Ruhlmann, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC09944A

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