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Issue 40, 2020
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Quantitative analysis of cannabinoids using benchtop NMR instruments

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Abstract

The quantification of cannabinoids is an essential part of cannabis profiling and testing, whether for medical or recreational use. As regulatory bodies continue to increase testing requirements for these products, it is crucial that alternative and effective analytical methods be developed. Herein, we describe the use of benchtop NMR instruments for the quantification of Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in a variety of cannabis concentrates and compare the values to those obtained using HPLC, the most common approach for the quantification of cannabinoids. Based on the discrepancies observed in test values from different laboratories using only HPLC, the value of orthogonal testing methods has been identified and is increasingly desired.

Graphical abstract: Quantitative analysis of cannabinoids using benchtop NMR instruments

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Article information


Submitted
08 Aug 2020
Accepted
07 Oct 2020
First published
07 Oct 2020

Anal. Methods, 2020,12, 4853-4857
Article type
Communication

Quantitative analysis of cannabinoids using benchtop NMR instruments

J. F. Araneda, T. Chu, M. C. Leclerc, S. D. Riegel and N. Spingarn, Anal. Methods, 2020, 12, 4853
DOI: 10.1039/D0AY01511C

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