Issue 16, 2020

High salt compatible oxyanion receptors by dual ion imprinting


The design of hosts for either cations or anions is complicated due to the competition for binding by the host or guest counterions. Imprinting relying on self-assembly offers the possibility to stabilize the guest and its counterion in a favorable geometry. We here report on a comprehensive supramolecular approach to anion receptor design relying on concurrent recognition of both anion and cation. This was achieved by high order complex imprinting of the disodium salt of phenyl-phosphonic acid in combination with neutral urea and sodium ion selective 18-crown-6 monomers. The polymers displayed enhanced affinity for the template or inorganic phosphate or sulfate in competitive aqueous buffers, with affinity and selectivity increasing with increasing ionic strength. The presence of engineered sites for both ionic species dramatically increases the salt uptake in strongly competitive media such as brine.

Graphical abstract: High salt compatible oxyanion receptors by dual ion imprinting

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Article information

Article type
Edge Article
23 Dec 2019
01 Apr 2020
First published
14 Apr 2020
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2020,11, 4246-4250

High salt compatible oxyanion receptors by dual ion imprinting

S. Shinde, M. Mansour, A. Incel, L. Mavliutova, C. Wierzbicka and B. Sellergren, Chem. Sci., 2020, 11, 4246 DOI: 10.1039/C9SC06508C

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