Graphene oxide as a green carbon material for cross-coupling of indoles with ethers via oxidation and the Friedel–Crafts reaction†
Abstract
Mild reaction conditions were developed to access 3,3′-bisindolylmethane derivatives with excellent regioselectivity at 25 °C based on a new graphene oxide (GO)-promoted alkylation strategy. To the best of our knowledge, these results constitute the first example of using a GO-based material as a carbon material to facilitate C(sp2)–C(sp3) bond formation.