Jump to main content
Jump to site search


A concise approach to the tricyclic framework of longipinane- and ent-longipinane-type sesquiterpenoids

Author affiliations

Abstract

A concise and efficient strategy for the synthesis of the common 6,6-dimethyltricyclic[5.4.0.02,8]undecane framework of longipinane- and ent-longipinane-type sesquiterpenoids has been developed. This approach features an intramolecular Diels–Alder reaction to construct the 6/7 cis-fused ring system and a Ti(III)-mediated reductive radical cyclization reaction to access the highly strained bridged cyclobutane moiety.

Graphical abstract: A concise approach to the tricyclic framework of longipinane- and ent-longipinane-type sesquiterpenoids

Back to tab navigation

Supplementary files

Publication details

The article was received on 13 Nov 2018, accepted on 13 Dec 2018 and first published on 20 Dec 2018


Article type: Research Article
DOI: 10.1039/C8QO01235K
Citation: Org. Chem. Front., 2019, Advance Article
  •   Request permissions

    A concise approach to the tricyclic framework of longipinane- and ent-longipinane-type sesquiterpenoids

    M. He, J. Yi, G. Zhao, P. Chen, D. Long, X. Hu, H. Li, X. Xie, X. Wang and X. She, Org. Chem. Front., 2019, Advance Article , DOI: 10.1039/C8QO01235K

Search articles by author

Spotlight

Advertisements