Jump to main content
Jump to site search

Issue 2, 2019
Previous Article Next Article

Cyanofluorination of vinyl ethers enabled by electron donor–acceptor complexes

Author affiliations

Abstract

An efficient and mild three-component cyanofluorination of vinyl ethers with Selectfluor and TMSCN is described. The reaction protocol is operationally simple, allowing the access to various α-alkoxy-β-fluoronitriles bearing quaternary α-carbons in good to excellent yields. The mechanistic studies indicated that the formation of an electron donor–acceptor (EDA) aggregate and a subsequent single electron transfer (SET) process might be involved in the reaction.

Graphical abstract: Cyanofluorination of vinyl ethers enabled by electron donor–acceptor complexes

Back to tab navigation

Supplementary files

Publication details

The article was received on 23 Oct 2018, accepted on 11 Dec 2018 and first published on 12 Dec 2018


Article type: Research Article
DOI: 10.1039/C8QO01143E
Citation: Org. Chem. Front., 2019,6, 241-244
  •   Request permissions

    Cyanofluorination of vinyl ethers enabled by electron donor–acceptor complexes

    J. Liu, Z. Zhu and F. Liu, Org. Chem. Front., 2019, 6, 241
    DOI: 10.1039/C8QO01143E

Search articles by author

Spotlight

Advertisements