Jump to main content
Jump to site search


Organocatalytic Enantioselective Conjugate Addition of Pyrazolin-5-ones to Arylomethylidene Malonates

Abstract

An efficient asymmetric organocatalytic conjugate addition reaction of pyrazolin-5-ones with arylomethylidene malonates has been successfully developed with the help of bifunctional Cinchona derived thiourea organocatalyst. The protocol provides straightforward access to the pyrazole substituted scaffolds in good yield under high stereocontrol.

Back to tab navigation

Supplementary files

Publication details

The article was received on 01 Aug 2019, accepted on 11 Oct 2019 and first published on 11 Oct 2019


Article type: Paper
DOI: 10.1039/C9OB01700C
Org. Biomol. Chem., 2019, Accepted Manuscript

  •   Request permissions

    Organocatalytic Enantioselective Conjugate Addition of Pyrazolin-5-ones to Arylomethylidene Malonates

    A. Sharma, V. Sharma and S. S. Chimni, Org. Biomol. Chem., 2019, Accepted Manuscript , DOI: 10.1039/C9OB01700C

Search articles by author

Spotlight

Advertisements