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HAP-01, the first chromogenic substrate for Aspergillus oryzae acid protease

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Abstract

The first chromogenic substrate for Aspergillus oryzae acid protease, ‘HAP-01’, was successfully developed after evaluating the substrate specificity of the enzyme. Furthermore, with HAP-01, digestion-triggered chromophore release was employed as a novel chromogenic technique.

Graphical abstract: HAP-01, the first chromogenic substrate for Aspergillus oryzae acid protease

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Publication details

The article was received on 07 Nov 2018, accepted on 19 Dec 2018 and first published on 20 Dec 2018


Article type: Communication
DOI: 10.1039/C8OB02766H
Citation: Org. Biomol. Chem., 2019, Advance Article
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    HAP-01, the first chromogenic substrate for Aspergillus oryzae acid protease

    T. Yoshiya, N. Yamashita, S. Tsuda, K. Oohigashi, S. Masuda, T. Kubodera and T. Akashi, Org. Biomol. Chem., 2019, Advance Article , DOI: 10.1039/C8OB02766H

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