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Issue 4, 2019
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Chemistry of detrifluoroacetylatively in situ generated fluoro-enolates

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Abstract

This review article comprehensively profiles all literature reports (2015–2018) related to the detrifluoroacetylative in situ generation of fluorine-containing enolates and their reactions with electrophilic reagents. The innovative facets of this unconventional methodology and its synthetic generality for the preparation of fluorine-containing compounds of high medicinal value are highlighted.

Graphical abstract: Chemistry of detrifluoroacetylatively in situ generated fluoro-enolates

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Publication details

The article was received on 15 Nov 2018, accepted on 13 Dec 2018 and first published on 13 Dec 2018


Article type: Review Article
DOI: 10.1039/C8OB02843E
Org. Biomol. Chem., 2019,17, 762-775

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    Chemistry of detrifluoroacetylatively in situ generated fluoro-enolates

    H. Mei, J. Liu, S. Fustero, R. Román, R. Ruzziconi, V. A. Soloshonok and J. Han, Org. Biomol. Chem., 2019, 17, 762
    DOI: 10.1039/C8OB02843E

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