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Chan-Lam N–arylation and C–H amination with heteroaromatic ring-NH: An approach to access extended-fused imidazo[1,2-a]-pyridines/pyrazines

Abstract

A di-amination strategy of areneboronic acids with heterocyclic azines via a tandem process of intermolecular Chan-Lam N–arylation and intramolecular arene C–H amination under copper(II)-mediated aerobic conditions has been realized. It constructs fused imidazole scaffold and affords a convenient route to access imidazo[1,2-a]-fused pyridine, pyrazine and other heterocycles

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Publication details

The article was received on 01 Oct 2019, accepted on 28 Nov 2019 and first published on 29 Nov 2019


Article type: Letter
DOI: 10.1039/C9NJ04966E
New J. Chem., 2019, Accepted Manuscript

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    Chan-Lam N–arylation and C–H amination with heteroaromatic ring-NH: An approach to access extended-fused imidazo[1,2-a]-pyridines/pyrazines

    S. K. Guchhait and M. Saini, New J. Chem., 2019, Accepted Manuscript , DOI: 10.1039/C9NJ04966E

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