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Synergic effect of plasmonic Gold Nanoparticles and Graphene Oxide on the enhancement of Glucose sensing

Abstract

In this study hybrid nanostructures of Au-graphene oxide (Au-GO) were synthesized via two-step process and used to modify the glassy carbon electrode (GCE) for electrochemical measurements of glucose. The modified electrode exhibits fast response less than 4s, low detection limit of 0.025 μM and high signal-to-noise ratio (S/N) of 3.5. The fabricated sensor shows a linear response in the large concentration range from 0.0025 mM to 15 mM with reproducible sensitivity of 84.53 μAcm-2mM-1, which is much higher than that of the individual Au, GO and previously reported GO/rGO based sensors. In addition, the biosensor shows excellent results for the human serum and agrees well with laboratory glucometer. Moreover, the glucose amount in selective commercially available food samples and fresh juices was also successfully measured. The biosensor reveals an excellent selectivity, thermal stability and reproducibility. The enhanced and efficient sensitivity of the developed Au-GO based biosensor may be owed to the synergic effects of the plasmonic Au-nanoparticles and GO. The performance of biosensor suggests that the reported Au-GO hybrid nanostructures can provide a novel platform to develop non-enzymatic biosensors for biomedical and industrial applications.

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Publication details

The article was received on 02 Sep 2019, accepted on 26 Oct 2019 and first published on 31 Oct 2019


Article type: Paper
DOI: 10.1039/C9NJ04532E
New J. Chem., 2019, Accepted Manuscript

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    Synergic effect of plasmonic Gold Nanoparticles and Graphene Oxide on the enhancement of Glucose sensing

    S. Tabussam , S. Naz, A. Nisar, H. Sun, S. Karim, M. Khan, S. Shahzada, A. U. Rahman and M. Ahmad, New J. Chem., 2019, Accepted Manuscript , DOI: 10.1039/C9NJ04532E

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