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Preparation and antibacterial behaviour of nanostructured Ag@SiO2–penicillin with silver nanoplates

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Abstract

In this study, we investigated the antibacterial properties of nanostructured Ag@SiO2–penicillin synthesized from triangular silver nanoplates (Ag NPs) against methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA) bacteria. The Ag@SiO2–penicillin nanoparticles contained approximately 33.2 wt% Ag as determined by ICP-OES. Grafting of about 2.8 wt% penicillin on Ag@SiO2 remarkably enhanced the bactericidal properties against MSSA and MRSA bacteria and showed no cell-death inducing effects towards the A431 cell line.

Graphical abstract: Preparation and antibacterial behaviour of nanostructured Ag@SiO2–penicillin with silver nanoplates

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Publication details

The article was received on 17 Jul 2019, accepted on 29 Sep 2019 and first published on 30 Sep 2019


Article type: Paper
DOI: 10.1039/C9NJ03727F
New J. Chem., 2019, Advance Article

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    Preparation and antibacterial behaviour of nanostructured Ag@SiO2–penicillin with silver nanoplates

    M. Malekzadeh, K. L. Yeung, M. Halali and Q. Chang, New J. Chem., 2019, Advance Article , DOI: 10.1039/C9NJ03727F

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