Jump to main content
Jump to site search

Issue 24, 2019
Previous Article Next Article

Identification and characterization of an anthrol reductase from Talaromyces islandicus (Penicillium islandicum) WF-38-12

Author affiliations

Abstract

An NADPH-dependent oxidoreductase from Talaromyces islandicus WF-38-12 has been identified through genome analysis. It has been shown to catalyze a regio- and stereoselective reduction of anthrols (formed in situ by the reduction of anthraquinones in the presence of Na2S2O4) to (R)-dihydroanthracenones, with high enantiomeric excess (>99%). The implications of results on the biosynthesis of deoxygenated (bis)anthraquinones and modified (bis)anthraquinones are discussed.

Graphical abstract: Identification and characterization of an anthrol reductase from Talaromyces islandicus (Penicillium islandicum) WF-38-12

Back to tab navigation

Supplementary files

Publication details

The article was received on 31 Aug 2019, accepted on 06 Nov 2019 and first published on 06 Nov 2019


Article type: Communication
DOI: 10.1039/C9GC03072G
Green Chem., 2019,21, 6594-6599

  •   Request permissions

    Identification and characterization of an anthrol reductase from Talaromyces islandicus (Penicillium islandicum) WF-38-12

    S. K. Singh, A. Mondal, N. Saha and S. M. Husain, Green Chem., 2019, 21, 6594
    DOI: 10.1039/C9GC03072G

Search articles by author

Spotlight

Advertisements