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Visible-light-induced radical cyclization of N-allylbenzamide with CF3SO2Na to trifluoromethylated dihydroisoquinolinones in water at room temperature

Abstract

A green and efficient strategy for the preparation of trifluoromethylated dihydroisoquinolinones via visible-light photoredox catalyzed radical cyclization of N‑allylbenzamide with CF3SO2Na in water at room temperature was developed. This photocatalytic reaction generated the desired products in good to excellent yields under simple and mild conditions.

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Publication details

The article was received on 20 Mar 2019, accepted on 13 May 2019 and first published on 16 May 2019


Article type: Paper
DOI: 10.1039/C9GC00938H
Green Chem., 2019, Accepted Manuscript

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    Visible-light-induced radical cyclization of N-allylbenzamide with CF3SO2Na to trifluoromethylated dihydroisoquinolinones in water at room temperature

    L. Zou, P. Li, B. Wang and L. Wang, Green Chem., 2019, Accepted Manuscript , DOI: 10.1039/C9GC00938H

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