Volume 219, 2019

Multivalent glycan arrays


Glycan microarrays have become a powerful technology to study biological processes, such as cell–cell interaction, inflammation, and infections. Yet, several challenges, especially in multivalent display, remain. In this introductory lecture we discuss the state-of-the-art glycan microarray technology, with emphasis on novel approaches to access collections of pure glycans and their immobilization on surfaces. Future directions to mimic the natural glycan presentation on an array format, as well as in situ generation of combinatorial glycan collections, are discussed.

Graphical abstract: Multivalent glycan arrays

Article information

Article type
11 Jun 2019
26 Jun 2019
First published
12 Jul 2019
This article is Open Access
Creative Commons BY license

Faraday Discuss., 2019,219, 9-32

Multivalent glycan arrays

M. Mende, V. Bordoni, A. Tsouka, F. F. Loeffler, M. Delbianco and P. H. Seeberger, Faraday Discuss., 2019, 219, 9 DOI: 10.1039/C9FD00080A

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