Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 13, 2019
Previous Article Next Article

Co-crystallization and polymorphic behaviour of 5-fluorouracil

Author affiliations

Abstract

Syntheses and single-crystal characterization of two co-crystalline 5-fluorouracil compounds with nontoxic co-formers of the GRAS list, succinic acid and adipic acid, are presented. Furthermore, the target-oriented synthon approach from methanol or ethanol (technical grade) to polymorphic form II, which is hitherto only accessible from dry nitromethane, is described.

Graphical abstract: Co-crystallization and polymorphic behaviour of 5-fluorouracil

Back to tab navigation

Supplementary files

Article information


Submitted
05 Oct 2018
Accepted
12 Nov 2018
First published
13 Nov 2018

CrystEngComm, 2019,21, 2130-2134
Article type
Paper

Co-crystallization and polymorphic behaviour of 5-fluorouracil

D. D. Enkelmann, J. Handelmann, C. Schauerte and K. Merz, CrystEngComm, 2019, 21, 2130
DOI: 10.1039/C8CE01692E

Social activity

Search articles by author

Spotlight

Advertisements