The terahertz dynamics interfaces to ion–lipid interaction confined in phospholipid reverse micelles

Abstract

The terahertz dynamics of water nanodroplets confined in phospholipid reverse micelles have been developed as a probe to explore the interactions of metal ions with lipid membrane interfaces. The terahertz absorption coefficients of reverse micelles vary greatly with different Cu²⁺ concentrations and with different headgroups. The results proved that the metal ion effects on water dynamics near a membrane surface can be detected via terahertz spectroscopy, thus providing a novel tool for investigating ion–lipid interactions.