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Smart engineering of a dual-DNA machine with high signal-to-noise ratio for one-pot robust and sensitive miRNA signaling

Abstract

A target triggered dual-DNA machine, consisting of one rolling circle amplification (RCA)-based circular DNA machine (RCA-CDM) and one cyclical strand displacement amplification (CSDA)-based bidirectional DNA machine (CSDA-BDM), was developed for robustly miRNA determination.

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Publication details

The article was received on 22 Sep 2019, accepted on 03 Nov 2019 and first published on 04 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC07442B
Chem. Commun., 2019, Accepted Manuscript

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    Smart engineering of a dual-DNA machine with high signal-to-noise ratio for one-pot robust and sensitive miRNA signaling

    P. Qin, L. Yao, J. Xu, G. Liu and W. Chen, Chem. Commun., 2019, Accepted Manuscript , DOI: 10.1039/C9CC07442B

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