Lan Li, Jiying Liang, Hao Luo, K. Ming Tam, Edmund C. M. Tse and Ying Li
Chem. Commun., 2019,55, 12340-12343
DOI:
10.1039/C9CC06251C,
Communication
A new nucleus-localized singlet oxygen generator was designed and synthesized. Its capability to label nucleus-localized biomolecules through spatially-restricted oxidation under visible light was validated using fluorescence confocal microscopy. Western blot and RT-qPCR were performed to verify the desirable spatial resolution through enriching chromatin-associated RNAs and proteins.