Shin-nosuke Nishimura, Nobuyuki Higashi and Tomoyuki Koga
Chem. Commun., 2019,55, 1498-1501
DOI:
10.1039/C8CC09051C,
Communication
A novel multiblock architecture composed of an alternating β-sheet forming oligopeptide and a thermo-responsive glycine-derived vinyl polymer was synthesized. The polymer exhibited lower critical solution temperature (LCST) behavior in water, unlike the behavior of a glycine-derived homopolymer, and formed nanoparticles through protein-mimicking folding driven by thermal cycle-induced β-sheet formation.