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Magnetic carbon nanotubes grafted with smart polymer brushes for highly efficient enantioseparation of tryptophan enantiomers

Abstract

We herein report one novel type of chiral carbon nanotubes nanomaterials (MCNTs-PNG-CD) based on smart polymer brushes grafted magnetic carbon nanotubes (MCNTs) for highly efficient chiral recognition and separation of tryptophan enantiomers (DL-Trp). The grafted PNG-CD smart polymer brushes are composed of thermosensitive poly(N-isopropyl acrylamide-co-glycidyl methacrylate) (PNG) copolymer chains with numerous appended beta-cyclodextrin (β-CD) units, which play a crucial role in efficient chiral discrimination and separation of DL-Trp. The PNG-CD were fabricated on the Fe3O4 nanoparticles-loaded carbon nanotubes (CNTs) by combining surface-initiated atom transfer radical polymerization (SI-ATRP) with a ring opening reaction. The MCNTs-PNG-CD were systematically characterized by transmission electron microscope (TEM), Fourier transform infrared (FT-IR) and Roman spectroscopy, thermogravimetric analysis (TGA), vibrating sample magnetometer (VSM) and elemental analysis (EA). The prepared MCNTs-PNG-CD demonstrate highly thermosensitive chiral recognition and enantioselectivity toward DL-Trp, which is based on host-guest interactions between β-CD units and L-tryptophan (L-Trp), and the thermosensitive volume phase transition of poly(N-isopropylacrylamide) (PNIPAM) chains. Operating temperature and initial concentrations of AAs are two significant factors that affect the chiral recognition and separation of DL-Trp. Furthermore, the obtained MCNTs-PNG-CD also exhibit satisfactory reusability and excellent magnetic separability from enantiomeric solutions. Such a multifunctional CNTs nanomaterial can serve as a high-performance nanoselector for direct enantioseparation of various chiral compounds.

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Publication details

The article was received on 14 Aug 2019, accepted on 10 Oct 2019 and first published on 11 Oct 2019


Article type: Paper
DOI: 10.1039/C9AY01736D
Anal. Methods, 2019, Accepted Manuscript

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    Magnetic carbon nanotubes grafted with smart polymer brushes for highly efficient enantioseparation of tryptophan enantiomers

    X. Yang, L. Lei, Z. Pen, H. Yu and C. Cheng, Anal. Methods, 2019, Accepted Manuscript , DOI: 10.1039/C9AY01736D

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