Issue 3, 2020

Making natural products from renewable feedstocks: back to the roots?

Abstract

Covering: up to mid-2019

This review highlights the utilization of biomass-derived building blocks in the total synthesis of natural products. An overview over several renewable feedstock classes, namely wood/lignin, cellulose, chitin and chitosan, fats and oils, as well as terpenes, is given, covering the time span from the initial beginning of natural product synthesis until today. The focus is put on the origin of the employed carbon atoms and on the nature of the complex structures that were assembled therefrom. The emerging trend of turning away from petrochemically derived starting materials back to bio-based resources, just as seen in the early days of total synthesis, shall be demonstrated.

Graphical abstract: Making natural products from renewable feedstocks: back to the roots?

Article information

Article type
Review Article
Submitted
03 Jul 2019
First published
18 Oct 2019
This article is Open Access
Creative Commons BY license

Nat. Prod. Rep., 2020,37, 380-424

Making natural products from renewable feedstocks: back to the roots?

J. Kühlborn, J. Groß and T. Opatz, Nat. Prod. Rep., 2020, 37, 380 DOI: 10.1039/C9NP00040B

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