Jump to main content
Jump to site search

Issue 87, 2019
Previous Article Next Article

First access to a mycolic acid-based bioorthogonal reporter for the study of the mycomembrane and mycoloyltransferases in Corynebacteria

Author affiliations

Abstract

In this study, we report the first synthesis of an alkyne-based trehalose monomycolate probe containing a β-hydroxylated fatty acid and an α-branched chain similar to those of the natural mycolic acid. We demonstrate its utility for the labeling of the mycomembrane of Corynebacteria as well as for the study of mycoloyltransferases.

Graphical abstract: First access to a mycolic acid-based bioorthogonal reporter for the study of the mycomembrane and mycoloyltransferases in Corynebacteria

Back to tab navigation

Supplementary files

Article information


Submitted
24 Jul 2019
Accepted
26 Sep 2019
First published
27 Sep 2019

Chem. Commun., 2019,55, 13074-13077
Article type
Communication

First access to a mycolic acid-based bioorthogonal reporter for the study of the mycomembrane and mycoloyltransferases in Corynebacteria

E. Lesur, A. Baron, C. Dietrich, M. Buchotte, G. Doisneau, D. Urban, J. Beau, N. Bayan, B. Vauzeilles, D. Guianvarc’h and Y. Bourdreux, Chem. Commun., 2019, 55, 13074
DOI: 10.1039/C9CC05754D

Social activity

Search articles by author

Spotlight

Advertisements