CO2-Acidolysis of iminoboronate ester based polymersomes

Ruidong Cheng; Guo Li; Li Fan; Zhaotie Liu; Zhongwen Liu; Jinqiang Jiang

doi:10.1039/C8TB02496K

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

CO₂-Acidolysis of iminoboronate ester based polymersomes†

Ruidong Cheng,^a Guo Li,*^a Li Fan,*^b Zhaotie Liu,

^a Zhongwen Liu^a and Jinqiang Jiang

*^a

Author affiliations

* Corresponding authors

^a Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi’an, Shaanxi Province, P. R. China
E-mail: liguo@snnu.edu.cn, jiangjq@snnu.edu.cn

^b Department of Pharmaceutical Analysis, School of Pharmacy, Fourth Military Medical University, Xi’an, Shaanxi Province, P. R. China
E-mail: xxfanny@fmmu.edu.cn

Abstract

Due to the very weak acidity of CO₂ in water, it is highly interesting to fabricate CO₂-responsive polymersomes which have both CO₂-protonatable tertiary amines and CO₂-hydrolyzable iminoboronate-linked drugs. Upon CO₂ addition, amine protonation and iminoboronate hydrolysis simultaneously occur, leading to prominent vesicle disassembly and a tunable release feature.

Download options Please wait...

Supplementary files

Supplementary information PDF (1362K)

Article information

DOI: https://doi.org/10.1039/C8TB02496K
Article type: Communication
Submitted: 23 Sep 2018
Accepted: 22 Oct 2018
First published: 22 Oct 2018

Download Citation

J. Mater. Chem. B, 2018,6, 7800-7804

Permissions

Request permissions

CO₂-Acidolysis of iminoboronate ester based polymersomes

R. Cheng, G. Li, L. Fan, Z. Liu, Z. Liu and J. Jiang, J. Mater. Chem. B, 2018, 6, 7800 DOI: 10.1039/C8TB02496K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Journal of Materials Chemistry B