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CO2-Acidolysis of iminoboronate ester based polymersomes

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Abstract

Due to the very weak acidity of CO2 in water, it is highly interesting to fabricate CO2-responsive polymersomes which have both CO2-protonatable tertiary amines and CO2-hydrolyzable iminoboronate-linked drugs. Upon CO2 addition, amine protonation and iminoboronate hydrolysis simultaneously occur, leading to prominent vesicle disassembly and a tunable release feature.

Graphical abstract: CO2-Acidolysis of iminoboronate ester based polymersomes

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Publication details

The article was received on 23 Sep 2018, accepted on 22 Oct 2018 and first published on 22 Oct 2018


Article type: Communication
DOI: 10.1039/C8TB02496K
Citation: J. Mater. Chem. B, 2018, Advance Article
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    CO2-Acidolysis of iminoboronate ester based polymersomes

    R. Cheng, G. Li, L. Fan, Z. Liu, Z. Liu and J. Jiang, J. Mater. Chem. B, 2018, Advance Article , DOI: 10.1039/C8TB02496K

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