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Issue 45, 2018
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Synergistic effects between silicon nanowires and doxorubicin at non-toxic doses lead to high-efficacy destruction of cancer cells

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Abstract

We herein provide a synergistic chemotherapeutic strategy by combining silicon nanowires (SiNWs) and doxorubicin (DOX) at nontoxic doses, suitable for high-efficacy destruction of cancer cells. The presented synergistic method can ruin tumors by destroying the cytoskeleton, arresting the cell cycle in the G2 phase, and damaging the mitochondria to release cytochrome C.

Graphical abstract: Synergistic effects between silicon nanowires and doxorubicin at non-toxic doses lead to high-efficacy destruction of cancer cells

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Publication details

The article was received on 07 Aug 2018, accepted on 15 Oct 2018 and first published on 17 Oct 2018


Article type: Communication
DOI: 10.1039/C8TB02070A
Citation: J. Mater. Chem. B, 2018,6, 7378-7382
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    Synergistic effects between silicon nanowires and doxorubicin at non-toxic doses lead to high-efficacy destruction of cancer cells

    B. Chu, F. Peng, H. Wang, Y. Su and Y. He, J. Mater. Chem. B, 2018, 6, 7378
    DOI: 10.1039/C8TB02070A

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