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Issue 31, 2018
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Metal-free heterogeneous and mesoporous biogenic graphene-oxide nanoparticle-catalyzed synthesis of bioactive benzylpyrazolyl coumarin derivatives

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Abstract

We report the preparation of graphene oxide nanoparticles (GONPs), a metal-free, heterogeneous, non-toxic, reusable and mesoporous green-(acid)-catalyst obtained by sugar carbonization through a micro-wave chemical synthesis method for the synthesis of bio-active benzylpyrazolyl coumarin derivatives (BCDs) under thermal conditions (50 °C) in ethanol solvent. The obtained products were purified by re-crystallization from ethanol, assuring usability of GONPs in multicomponent reactions (MCRs) that could find wide application in the synthesis of a variety of biologically potent molecules of therapeutic significance.

Graphical abstract: Metal-free heterogeneous and mesoporous biogenic graphene-oxide nanoparticle-catalyzed synthesis of bioactive benzylpyrazolyl coumarin derivatives

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Publication details

The article was received on 18 Nov 2017, accepted on 03 May 2018 and first published on 14 May 2018


Article type: Paper
DOI: 10.1039/C7RA12550J
Citation: RSC Adv., 2018,8, 17373-17379
  • Open access: Creative Commons BY-NC license
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    Metal-free heterogeneous and mesoporous biogenic graphene-oxide nanoparticle-catalyzed synthesis of bioactive benzylpyrazolyl coumarin derivatives

    T. A. J. Siddiqui, B. G. Ghule, S. Shaikh, Pritamkumar V. Shinde, K. C. Gunturu, P. K. Zubaidha, J. M. Yun, C. O'Dwyer, R. S. Mane and K. H. Kim, RSC Adv., 2018, 8, 17373
    DOI: 10.1039/C7RA12550J

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