Jump to main content
Jump to site search


Red-Light Responsive Molecular Encapsulation in Water: An Ideal Combination of Photochemistry and Host-Guest Interaction

Abstract

A major limitation in the application of light-responsive host-guest complex-based photoresponsive materials in living organisms is the relatively lack of reliable photocontrollable recognition motifs activated beyond UV light, especially by the light within biological window (650 - 1450 nm). Herein, we portray the long wavelength light-responsive cucurbit[8]uril (CB[8])-mediated binary host-guest complexes, in which the encapsulated photoisomerizable azobenzene-derived guests exhibit high E→Z photoisomerzation ratio upon the irradiation of the yellow (> 500 nm) or red (650 nm) lights. The non-irradiated binary host-guest complex could be further severed as supramolecular nanocontainer to uptake a second guest (e.g. selected drug molecules). Moreover, “on command” release of the non-photoactive molecular cargo could be triggered by irradiating the resulting CB[8]-mediated heteroternary host-guest complex with yellow or red lights. Benefiting from activation within the biological window with high photoisomerization ratio, the specific red-light responsive CB[8]-mediated heteroternary host-guest complexation is expected to be a promising tool in the widely application of photopharmacotherapy, drug delivery and biocompatible dynamic materials.

Back to tab navigation

Supplementary files

Publication details

The article was received on 25 Oct 2018, accepted on 21 Nov 2018 and first published on 22 Nov 2018


Article type: Research Article
DOI: 10.1039/C8QO01157E
Citation: Org. Chem. Front., 2018, Accepted Manuscript
  •   Request permissions

    Red-Light Responsive Molecular Encapsulation in Water: An Ideal Combination of Photochemistry and Host-Guest Interaction

    K. Zhang, J. Wei, T. Jin, Y. Yin, X. Jiang, S. Zheng, J. Cui, L. Liu, T. Zhan and L. Kong, Org. Chem. Front., 2018, Accepted Manuscript , DOI: 10.1039/C8QO01157E

Search articles by author

Spotlight

Advertisements