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Development of a FRET-based ratiometric fluorescent probe to monitor the changes in palladium(II) in aqueous solution and living cells

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Abstract

The enrichment of palladium ions in organisms can harm organisms to a great extent. It is necessary and critical to develop molecular tools that can ratiometrically image Pd2+ in living cells. Herein, we have developed a new FRET-based ratiometric fluorescent probe (CR-Pd) for the specific determination of Pd2+ in living cells. Moreover, fluorescence imaging shows that CR-Pd could be used as a probe for the ratiometric visualization of Pd2+ in mitochondria.

Graphical abstract: Development of a FRET-based ratiometric fluorescent probe to monitor the changes in palladium(ii) in aqueous solution and living cells

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Publication details

The article was received on 25 Sep 2018, accepted on 21 Nov 2018 and first published on 22 Nov 2018


Article type: Letter
DOI: 10.1039/C8NJ04866E
Citation: New J. Chem., 2019, Advance Article
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    Development of a FRET-based ratiometric fluorescent probe to monitor the changes in palladium(II) in aqueous solution and living cells

    L. Wang, M. Ren, Z. Li, L. Dai and W. Lin, New J. Chem., 2019, Advance Article , DOI: 10.1039/C8NJ04866E

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