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Issue 10, 2018
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High-throughput countercurrent microextraction in passive mode

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Although microextraction is much more efficient than conventional macroextraction, its practical application has been limited by low throughputs and difficulties in constructing robust countercurrent microextraction (CCME) systems. In this work, a robust CCME process was established based on a novel passive microextractor with four units without any moving parts. The passive microextractor has internal recirculation and can efficiently mix two immiscible liquids. The hydraulic characteristics as well as the extraction and back-extraction performance of the passive CCME were investigated experimentally. The recovery efficiencies of the passive CCME were 1.43–1.68 times larger than the best values achieved using cocurrent extraction. Furthermore, the total throughput of the passive CCME developed in this work was about one to three orders of magnitude higher than that of other passive CCME systems reported in the literature. Therefore, a robust CCME process with high throughputs has been successfully constructed, which may promote the application of passive CCME in a wide variety of fields.

Graphical abstract: High-throughput countercurrent microextraction in passive mode

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Publication details

The article was received on 22 Nov 2017, accepted on 11 Apr 2018 and first published on 13 Apr 2018

Article type: Paper
DOI: 10.1039/C7LC01244F
Citation: Lab Chip, 2018,18, 1471-1484
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    High-throughput countercurrent microextraction in passive mode

    T. Xie and C. Xu, Lab Chip, 2018, 18, 1471
    DOI: 10.1039/C7LC01244F

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