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Internalization of the pseudorabies virus via macropinocytosis analyzed by quantum dot-based single-virus tracking

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Abstract

With the aid of the single-virus tracking technique and the quantum dot-labeling strategy, the internalization of the pseudorabies virus (PrV) has been visualized in real time. The results demonstrate that macropinocytosis can be considered as a major pathway for PrV entering HeLa cells, which facilitates the development of therapeutics for virus-triggered diseases.

Graphical abstract: Internalization of the pseudorabies virus via macropinocytosis analyzed by quantum dot-based single-virus tracking

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Publication details

The article was received on 12 Jul 2018, accepted on 12 Sep 2018 and first published on 14 Sep 2018


Article type: Communication
DOI: 10.1039/C8CC05614E
Citation: Chem. Commun., 2018, Advance Article
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    Internalization of the pseudorabies virus via macropinocytosis analyzed by quantum dot-based single-virus tracking

    C. Lv, Y. Lin, E. Sun, B. Tang, J. Ao, J. Wang, Z. Zhang, Z. Zheng, H. Wang and D. Pang, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC05614E

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