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Issue 79, 2018
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Enzyme-immobilized metal–organic framework nanosheets as tandem catalysts for the generation of nitric oxide

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Abstract

An enzyme-immobilized metal–organic framework (MOF) nanosheet system was developed as a tandem catalyst, which converted glucose into gluconic acid and H2O2, and sequentially the latter could be used to catalyze the oxidation of L-arginine to generate nitric oxide in the presence of porphyrinic MOFs as artificial enzymes under physiological pH, showing great potential in cancer depleting glucose for starving-like/gas therapy.

Graphical abstract: Enzyme-immobilized metal–organic framework nanosheets as tandem catalysts for the generation of nitric oxide

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Publication details

The article was received on 25 Jun 2018, accepted on 10 Sep 2018 and first published on 12 Sep 2018


Article type: Communication
DOI: 10.1039/C8CC05068F
Citation: Chem. Commun., 2018,54, 11176-11179
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    Enzyme-immobilized metal–organic framework nanosheets as tandem catalysts for the generation of nitric oxide

    P. Ling, C. Qian, F. Gao and J. Lei, Chem. Commun., 2018, 54, 11176
    DOI: 10.1039/C8CC05068F

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