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Issue 4, 2017
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Efficient synthesis of 5-(chloromethyl)furfural (CMF) from high fructose corn syrup (HFCS) using continuous flow processing

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Abstract

Using continuous flow processing the synthesis of 5-(chloromethyl)furfural (CMF) from both solid sugars and high fructose corn syrup (HFCS) was achieved. The use of HFCS allows for a convenient liquid sugar feedstock, which in turn through our improved three pump system, allows for production of CMF with no additional handling of stock solutions. Extensive reaction optimisation was also carried out with large increases in reaction efficiency achieved over existing batch processes.

Graphical abstract: Efficient synthesis of 5-(chloromethyl)furfural (CMF) from high fructose corn syrup (HFCS) using continuous flow processing

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Article information


Submitted
14 Mar 2017
Accepted
12 Jun 2017
First published
12 Jun 2017

React. Chem. Eng., 2017,2, 541-549
Article type
Paper

Efficient synthesis of 5-(chloromethyl)furfural (CMF) from high fructose corn syrup (HFCS) using continuous flow processing

T. M. Kohl, B. Bizet, P. Kevan, C. Sellwood, J. Tsanaktsidis and C. H. Hornung, React. Chem. Eng., 2017, 2, 541
DOI: 10.1039/C7RE00039A

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