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Abstract | Cited by

A three component reaction with two different ketones and aromatic amines was firstly investigated. The difference in reactivity between ordinary ketones and ketone esters allowed for the production of 1,2-DHQs efficiently. The possible Skraup reaction with 2 equiv. of the same ketones was prohibited due to the fast formation of imines.

Graphical abstract: A one pot three-component reaction for the preparation of dihydroquinolines with two different ketones and aromatic amines

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