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Issue 9, 2017
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Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

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Abstract

Hydrogen sulfide, an important gaseous signaling molecule in the human body, is known to protect cardiomyocytes from ischemia, a condition characterized by insufficient oxygen supply to the cells. Here we show that a nanosized H2S donor micelle releases H2S intracellularly and prevents cardiomyocyte apoptosis in an in vitro ischemia model.

Graphical abstract: Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

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Article information


Submitted
30 Mar 2017
Accepted
23 Jun 2017
First published
28 Jun 2017

Mol. BioSyst., 2017,13, 1705-1708
Article type
Communication

Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

T. Takatani-Nakase, M. Katayama, C. Matsui, K. Hanaoka, A. J. van der Vlies, K. Takahashi, I. Nakase and U. Hasegawa, Mol. BioSyst., 2017, 13, 1705 DOI: 10.1039/C7MB00191F

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