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Issue 9, 2017
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Understanding the role of tyrosine in glycogenin

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We explored the molecular basis of tyrosine as the docking amino acid for the first glucose molecule during the synthesis of glycogen. The IR spectra show that the aromatic ring acts as bait to keep the position where the next glucose unit has to bind clear, by luring non-desirable molecules towards the aromatic ring. Only, α-/β-glucose shows particular affinity for the O3H and O4H moieties.

Graphical abstract: Understanding the role of tyrosine in glycogenin

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The article was received on 17 May 2017, accepted on 26 Jun 2017 and first published on 30 Jun 2017

Article type: Communication
DOI: 10.1039/C7MB00293A
Citation: Mol. BioSyst., 2017,13, 1709-1712
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    Understanding the role of tyrosine in glycogenin

    A. Camiruaga, I. Usabiaga, A. Insausti, E. J. Cocinero, I. León and J. A. Fernández, Mol. BioSyst., 2017, 13, 1709
    DOI: 10.1039/C7MB00293A

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