Issue 32, 2017

A selective and light-up fluorescent probe for β-galactosidase activity detection and imaging in living cells based on an AIE tetraphenylethylene derivative

Abstract

An aggregation induced emission (AIE) based bioimaging probe, TPE-Gal, was designed for light-up imaging of β-galactosidase in living cells. The applicability of TPE-Gal in imaging endogenous β-galactosidase activity was confirmed in OVCAR-3 cells.

Graphical abstract: A selective and light-up fluorescent probe for β-galactosidase activity detection and imaging in living cells based on an AIE tetraphenylethylene derivative

Supplementary files

Article information

Article type
Communication
Submitted
11 Jan 2017
Accepted
29 Mar 2017
First published
29 Mar 2017

Chem. Commun., 2017,53, 4505-4508

A selective and light-up fluorescent probe for β-galactosidase activity detection and imaging in living cells based on an AIE tetraphenylethylene derivative

G. Jiang, G. Zeng, W. Zhu, Y. Li, X. Dong, G. Zhang, X. Fan, J. Wang, Y. Wu and B. Z. Tang, Chem. Commun., 2017, 53, 4505 DOI: 10.1039/C7CC00249A

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