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Issue 43, 2017
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Porphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles for two-photon photodynamic therapy or photoacoustic imaging

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Abstract

Porphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles (BSPOR and BSPHT) were prepared. Their endocytosis in MCF-7 cancer cells was shown with two-photon excited fluorescence (TPEF) imaging. With two-photon excited photodynamic therapy (TPE-PDT), BSPOR was more phototoxic than BSPHT, which in contrast displayed a very high signal for photoacoustic imaging in mice.

Graphical abstract: Porphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles for two-photon photodynamic therapy or photoacoustic imaging

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Supplementary files

Article information


Submitted
28 Jun 2017
Accepted
01 Oct 2017
First published
03 Oct 2017

Nanoscale, 2017,9, 16622-16626
Article type
Communication

Porphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles for two-photon photodynamic therapy or photoacoustic imaging

C. Mauriello-Jimenez, M. Henry, D. Aggad, L. Raehm, X. Cattoën, M. Wong Chi Man, C. Charnay, S. Alpugan, V. Ahsen, D. K. Tarakci, P. Maillard, M. Maynadier, M. Garcia, F. Dumoulin, M. Gary-Bobo, J. Coll, V. Josserand and J. Durand, Nanoscale, 2017, 9, 16622
DOI: 10.1039/C7NR04677D

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