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Issue 10, 2017
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Hydrophobicity determines the fate of self-assembled fluorescent nanoparticles in cells

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Abstract

The fate of small molecule nanoparticles (SMNPs) composed of self-assembling intrinsically fluorescent π-conjugated oligomers was studied in cells as a function of side-chain hydrophobicity. While the hydrophobic SMNPs remained intact upon cellular uptake, the more hydrophilic SMNPs disassembled and dispersed throughout the cytosol.

Graphical abstract: Hydrophobicity determines the fate of self-assembled fluorescent nanoparticles in cells

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Article information


Submitted
02 Nov 2016
Accepted
09 Jan 2017
First published
10 Jan 2017

This article is Open Access

Chem. Commun., 2017,53, 1626-1629
Article type
Communication

Hydrophobicity determines the fate of self-assembled fluorescent nanoparticles in cells

A. H. A. M. van Onzen, L. Albertazzi, A. P. H. J. Schenning, L. Milroy and L. Brunsveld, Chem. Commun., 2017, 53, 1626
DOI: 10.1039/C6CC08793K

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