Issue 25, 2016
From the journal:

RSC Advances

Palladium-catalyzed decarboxylative ortho-aroylation of N-acetyl-1,2,3,4-tetrahydroquinolines with α-oxoarylacetic acids†

Lu Han,ab   Yahui Wang,c   He Song,ab   Huatao Han,ab   Lulu Wang,ab   Wenyi Chu*ab  and  Zhizhong Sun*ab  

* Corresponding authors

a School of Chemistry and Materials Science, Heilongjiang University, Harbin 150080, P. R. China
E-mail: wenyichu@hlju.edu.cn, sunzz@hlju.edu.cn

b Key Laboratory of Chemical Engineering Process and Technology for High-efficiency Conversion, College of Heilongjiang Province, Harbin 150080, P. R. China

c Harbin Environmental Monitoring Central Station, Harbin 150076, P. R. China

Abstract

A mild, practical and efficient palladium-catalyzed decarboxylative ortho-aroylation of N-acetyl-1,2,3,4-tetrahydroquinolines with α-oxoarylacetic acids via C–H bond activation is described. This protocol provides efficient access to a series of C8-aroyl terahydroquinolines.

Graphical abstract: Palladium-catalyzed decarboxylative ortho-aroylation of N-acetyl-1,2,3,4-tetrahydroquinolines with α-oxoarylacetic acids

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Article information

DOI
https://doi.org/10.1039/C6RA00163G
Article type
Paper
Submitted
04 Jan 2016
Accepted
05 Feb 2016
First published
08 Feb 2016

RSC Adv., 2016,6, 20637-20643

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Palladium-catalyzed decarboxylative ortho-aroylation of N-acetyl-1,2,3,4-tetrahydroquinolines with α-oxoarylacetic acids

L. Han, Y. Wang, H. Song, H. Han, L. Wang, W. Chu and Z. Sun, RSC Adv., 2016, 6, 20637 DOI: 10.1039/C6RA00163G

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