Jump to main content
Jump to site search

Issue 85, 2016
Previous Article Next Article

Structural regulation by a G-quadruplex ligand increases binding abilities of G-quadruplex-forming aptamers

Author affiliations

Abstract

We report that a G-quadruplex-specific compound induced structural changes in G-quadruplex-forming DNA aptamers and stabilized the folded structures, making them suitable for targeted proteins and enhancing their binding properties.

Graphical abstract: Structural regulation by a G-quadruplex ligand increases binding abilities of G-quadruplex-forming aptamers

Back to tab navigation

Supplementary files

Publication details

The article was received on 16 Sep 2016, accepted on 29 Sep 2016 and first published on 30 Sep 2016


Article type: Communication
DOI: 10.1039/C6CC07552E
Citation: Chem. Commun., 2016,52, 12646-12649
  •   Request permissions

    Structural regulation by a G-quadruplex ligand increases binding abilities of G-quadruplex-forming aptamers

    K. Tsukakoshi, Y. Ikuta, K. Abe, W. Yoshida, K. Iida, Y. Ma, K. Nagasawa, K. Sode and K. Ikebukuro, Chem. Commun., 2016, 52, 12646
    DOI: 10.1039/C6CC07552E

Search articles by author

Spotlight

Advertisements