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Issue 45, 2016
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Positron detection in silica monoliths for miniaturised quality control of PET radiotracers

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Abstract

We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [68Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control. The system achieved a far superior signal-to-noise ratio compared to conventional sodium iodide-based radio-HPLC detection and allowed real-time visualisation of positrons in the monolith.

Graphical abstract: Positron detection in silica monoliths for miniaturised quality control of PET radiotracers

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Supplementary files

Article information


Submitted
22 Jan 2016
Accepted
16 Mar 2016
First published
16 Mar 2016

This article is Open Access

Chem. Commun., 2016,52, 7221-7224
Article type
Communication
Author version available

Positron detection in silica monoliths for miniaturised quality control of PET radiotracers

M. D. Tarn, D. Maneuski, R. Alexander, N. J. Brown, V. O’Shea, S. L. Pimlott, N. Pamme and S. J. Archibald, Chem. Commun., 2016, 52, 7221
DOI: 10.1039/C6CC00660D

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