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Issue 6, 2016
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Dynamic control of cell adhesion on a stiffness-tunable substrate for analyzing the mechanobiology of collective cell migration

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Abstract

A method was developed for photocontrolling cell adhesion on a gel substrate with defined mechanical properties. Precise patterning of geometrically controlled cell clusters and their migration induction became possible by spatiotemporally controlled photo-irradiation of the substrate. The clusters exhibited unique collective motion that depended on substrate stiffness and cluster geometry.

Graphical abstract: Dynamic control of cell adhesion on a stiffness-tunable substrate for analyzing the mechanobiology of collective cell migration

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Publication details

The article was received on 09 Feb 2016, accepted on 29 Mar 2016 and first published on 06 Apr 2016


Article type: Communication
DOI: 10.1039/C6BM00100A
Citation: Biomater. Sci., 2016,4, 933-937
  • Open access: Creative Commons BY-NC license
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    Dynamic control of cell adhesion on a stiffness-tunable substrate for analyzing the mechanobiology of collective cell migration

    M. Kamimura, M. Sugawara, S. Yamamoto, K. Yamaguchi and J. Nakanishi, Biomater. Sci., 2016, 4, 933
    DOI: 10.1039/C6BM00100A

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