Issue 22, 2016

Homogeneous rhodium(i)-catalysis in de novo heterocycle syntheses


Recent research has led to the development of mild, efficient and selective catalytic systems based on Rh(I) complexes. This review summarises the applications of these catalysts to the synthesis of heterocycles from simple building blocks. Included herein are approaches based on cycloisomerisation, cycloaddition, hydroacylation and hydroarylation reactions, as well as various tandem and domino procedures and carbonylation processes.

Graphical abstract: Homogeneous rhodium(i)-catalysis in de novo heterocycle syntheses

Article information

Article type
Review Article
19 Apr 2016
12 May 2016
First published
20 May 2016
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2016,14, 4986-5000

Author version available

Homogeneous rhodium(I)-catalysis in de novo heterocycle syntheses

J. D. Neuhaus and M. C. Willis, Org. Biomol. Chem., 2016, 14, 4986 DOI: 10.1039/C6OB00835F

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