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Issue 88, 2016

Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

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Abstract

A novel method for the introduction of a single protected amine-functional monomer at the chain end of RAFT polymers has been developed. This monomer addition, in concert with native chemical ligation, facilitated the development of a simple and versatile method for the end-functionalization of polymers with peptides.

Graphical abstract: Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

Supplementary files

Article information


Submitted
21 Jul 2016
Accepted
21 Sep 2016
First published
23 Sep 2016

Chem. Commun., 2016,52, 12952-12955
Article type
Communication

Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

N. Isahak, G. Gody, L. R. Malins, N. J. Mitchell, R. J. Payne and S. Perrier, Chem. Commun., 2016, 52, 12952 DOI: 10.1039/C6CC06010B

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