Immobilization of nattokinase-loaded red blood cells on the surface of superhydrophobic polypropylene targeting fibrinolytic performance

Abstract

A platform for capture and release of drug-loaded red blood cells (RBCs) is demonstrated by utilizing polymer grafted superhydrophobic polypropylene (PP). Combined with micro/nanobinary structures, thermoresponsive polymers, and lectin–saccharides recognition, this platform enables highly efficient capture and release of RBCs loaded with nattokinase, which endows PP with potent fibrinolytic ability.