Glycoprotein recognition by water-compatible core–shell polymeric submicron particles

Abstract

Biocompatible boronate core–shell polymeric particles were grown in a unique polymerization system via a one-pot strategy making full use of the residual soluble boronate oligomer to in situ build the core–shell structure. The obtained submicron particles were shown to exhibit excellent recognition affinity toward glycoproteins with high binding capacity and specificity.