P. Ahlers, H. Frisch and P. Besenius
Polym. Chem., 2015,6, 7245-7250
DOI:
10.1039/C5PY01241D,
Communication
Charged phenylalanine-rich dendritic peptides form highly stable and pH-switchable rod-like supramolecular copolymers, when co-assembled with a matching oppositely charged dendritic comonomer. Here, we demonstrate that by mismatching a strong with a weak β-sheet encoded comonomer, both the stability and the pH-triggered disassembly of the copolymers shifts drastically from pH 4.2 to biologically relevant pH 5.8.