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Mixed core nanoparticles were prepared from self-assembled statistical and block copolymers by controlling the solution temperature. An equal mass of statistical copolymers was loaded into block copolymer micelle cores. A chimeric core was also constructed by adjusting the physicochemical properties of the mixed statistical copolymers.

Graphical abstract: Temperature-responsive mixed core nanoparticle properties determined by the composition of statistical and block copolymers in the core

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