Issue 20, 2015

Indium-catalyzed oxidative cross-dehydrogenative coupling of chromenes with 1,3-dicarbonyls and aryl rings

Abstract

An effective indium-catalyzed oxidative cross-dehydrogenative coupling of electronically varied chromenes with 1,3-dicarbonyl compounds and aryl rings has been established. Both the C–H alkylation and arylation proceed smoothly at room temperature to afford diverse α-substituted chromene compounds in up to 91% yields. Besides these two types of C–H components, simple ketones like cyclohexanones also prove to be well tolerated.

Graphical abstract: Indium-catalyzed oxidative cross-dehydrogenative coupling of chromenes with 1,3-dicarbonyls and aryl rings

Supplementary files

Article information

Article type
Paper
Submitted
08 Feb 2015
Accepted
12 Apr 2015
First published
14 Apr 2015

Org. Biomol. Chem., 2015,13, 5710-5715

Indium-catalyzed oxidative cross-dehydrogenative coupling of chromenes with 1,3-dicarbonyls and aryl rings

F. Li, Z. Meng, J. Hua, W. Li, H. Lou and L. Liu, Org. Biomol. Chem., 2015, 13, 5710 DOI: 10.1039/C5OB00277J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements