5,5′-Diamino-BIPHEP ligands bearing small selector units for non-covalent binding of chiral analytes in solution

Abstract

A dynamic axially chiral BIPHEP-ligand with 3,5-dichlorobenzoyl amide selector units for non-covalent binding of phenylalanine derivatives has been developed. Interaction studies in solution were performed with rhodium(I) complexes under exclusion of the metal being involved in binding. (R_ax, S^Phe) and (S_ax, S^Phe) adducts were observed as significantly separated species in NMR spectroscopy.